Cyproheptadine is an antihistamine. Cyproheptadine blocks the effects of the naturally occurring chemical histamine in your body.
Cyproheptadine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.
Although not approved by the FDA for this purpose, cyproheptadine has been used to stimulate appetite in underweight patients.
Cyproheptadine may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about Periactin (cyproheptadine)?
Use caution when driving, operating machinery, or performing other hazardous activities. Cyproheptadine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking cyproheptadine.